2-oxo-1-[(substituted sulfonyl)amino]carbonyl]azetidines

Details 2-oxo-1-[(substituted sulfonyl)amino]carbonyl]azetidines 2-oxo-1-[(substituted sulfonyl)amino]carbonyl]azetidines

C - Chemistry, Metallurgy

07

D

167/222, 260/255

C07D 417/14 (2006.01) A61K 31/505 (2006.01)

Patent

CA 1323029

ABSTRACT This invention relates to 2-azetidinones of the formula: Image , or a pharmaceutically acceptable salt thereof, wherein R is Image or Image wherein A1 is a single bond, -NH-?-, -NH- or -NH-NH-?-, A2 is a single bond, -NH-, -CH2-CH2-NH-, or -?-NH-NH-, A3 is a single bond, -CH=CH-, -(CH2)t-, -NH-(CH2)p- or Image wherein t is 1, 2, 3 or 4 and p is 0 or 1, and A4 is a single bond, -CH2-, -NH-CH2-, or -N=CH-; R1 is - Image ; and R4 is Image , Image , Image ; said azetidinones having antibacterial activity.

584058

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