2-oxo-3-benzylbenzoxazol-2-one derivatives and related...

Details 2-oxo-3-benzylbenzoxazol-2-one derivatives and related... 2-oxo-3-benzylbenzoxazol-2-one derivatives and related...

C - Chemistry, Metallurgy

07

D

C07D 413/10 (2006.01) A61K 31/424 (2006.01) A61K 31/437 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 498/06 (2006.01)

Patent

CA 2689554

The invention relates to compounds of formula (I), wherein R1, R2, R3, R3', R4, R4', E1 E', E', and E'' have the meaning stated in claim (1) that are inhibitors of tyrosine kinases, particularly of Met kinase, and can be utilized, among other things, for the treatment of tumors.

L'invention concerne les composés de formule (I) dans laquelle R1, R2, R3, R3', R4, R4', E1 E', E' et E'' ont les significations indiquées dans la revendication (1), sont des inhibiteurs des tyrosine-kinases, notamment de la kinase MET et peuvent être utilisés, entre autres, dans le traitement de tumeurs.

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