2-phenanthridinyl carbapenem antibacterial agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 477/14 (2006.01) A61K 31/435 (2006.01) A61K 31/675 (2006.01) C07D 519/00 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2154276

The present invention relates to antibacterial agents of the carbapenem class, in which the 2-position sidechain is characterized by a phenanthridine moiety typically having a substituent attached to the nitrogen of the phenanthridine and substituted at other positions by various neutral substituents. When there is substitution on the nitrogen of the phenanthridine moiety that nitrogen is a charged quaternary nitrogen.

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