C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/506 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2719569
The present invention relates to 2-phenyl-4-cyclopropyl-pyrimidine derivatives and their use as P2Y12 receptor an-tagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mam-mals.
La présente invention concerne des dérivés de 2-phényl-4-cyclopropyl-pyrimidine et leur utilisation comme antagonistes du récepteur P2Y12 dans le traitement et/ou la prévention des maladies vasculaires périphériques, viscéro-vasculaires, hépato-vasculaires et réno-vasculaires, cardiovasculaires et cérébrovasculaires ou des états associés à lagrégation plaquettaire, y compris la thrombose chez les humains et les autres mammifères.
Caroff Eva
Meyer Emmanuel
Actelion Pharmaceuticals Ltd
Gowling Lafleur Henderson Llp
LandOfFree
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