C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 271/113 (2006.01) A61K 31/4245 (2006.01) A61P 25/00 (2006.01) C07D 413/12 (2006.01) C07D 471/08 (2006.01)
Patent
CA 2653771
The present invention relates to novel oxadiazole derivatives of formula (1) having pharmacological activity, processes for their preparation, compositions containing them and their use in the treatment of neurological, psychiatric disorders and gastrointestinal disorders through modulation of the nicotinic .alpha.7 receptor formula (I).
La présente invention concerne de nouveaux dérivés d'oxadiazole de formule (1) présentant une activité pharmacologique, leurs procédés de synthèse, des compositions les incluant et leur utilisation dans le traitement de troubles neurologiques, psychiatriques et gastro-intestinaux par modulation du récepteur nicotinique .alpha.7. Formule (I).
Coppo Frank Teen
Maskell Emma S. L.
Redshaw Sally
Skidmore John
Ward Robert William
Glaxo Group Limited
Gowling Lafleur Henderson Llp
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