2-phenyl-6-aminocarbonyl-pyrimidine derivatives

Details 2-phenyl-6-aminocarbonyl-pyrimidine derivatives 2-phenyl-6-aminocarbonyl-pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 239/34 (2006.01) A61K 31/506 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2664347

The invention relates to 2-phenyl-6-aminbcarbonyl-pyrimidine derivatives and their use as P2Y12 receptor antagonists in the treatment and/or prevention and/or treatment of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals. Formula (I).

La présente invention concerne des dérivés de 2-phényl-6-aminocarbonyl-pyrimidine et leur utilisation en tant qu'antagonistes de récepteur P2Y12 dans le traitement et/ou la prévention et/ou le traitement de maladies et états vasculaires périphériques, viscéro-, hépato- et rénovasculaires, cardiovasculaires et cérébrovasculaires associés à l'agrégation plaquettaire, tels que la thrombose chez les êtres humains et autres mammifères.

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