2-(phenylalkylhydrazono)-propionic acid derivatives and the...

Details 2-(phenylalkylhydrazono)-propionic acid derivatives and the... 2-(phenylalkylhydrazono)-propionic acid derivatives and the...

C - Chemistry, Metallurgy

07

D

260/477, 260/351

C07D 317/60 (2006.01) A61K 31/00 (2006.01) A61K 31/15 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/22 (2006.01) A61K 31/36 (2006.01) C07D 317/16 (2006.01) C07D 317/48 (2006.01) C07D 317/58 (2006.01)

Patent

CA 1106389

ABSTRACT OF THE DISCLOSURE New propionic acid derivatives are provided which exhibit a hypoglycaemic activity at a dosage level at which an inhibition of monoamino oxidases does not occur or does not occur to a substantial degree; the new derivatives have the formula (I):- Image (I) wherein R1 and R2, which can be the same or different, are hydrogen or halogen atoms, or trifluoromethyl, lower alkyl, hydroxyl, acyloxy or lower alkoxy radicals or together represent a methylenedioxy radical and X is a straight-chain, saturated or unsaturated aliphatic hydrocarbon radical containing 2 to 4 carbon atoms which is unsubstituted or substituted by a lower alkyl radical in the .beta.- or .gamma.-position to the nitrogen atom; and the pharmaceutically acceptable, physiologically compatible salts, esters and amides thereof; there are also provided processes for preparing the new compounds.

285770

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