C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/280, 260/277
C07D 401/12 (2006.01) C07C 205/37 (2006.01) C07D 209/48 (2006.01) C07D 233/50 (2006.01)
Patent
CA 1175434
ABSTRACT The novel imidazole derivatives of the general formula Image wherein R1, R2 and R3 independently of one another signify hydrogen, halogen, trifluoromethyl, nitro, lower alkyl or lower alkylthio, one of R4 and R5 signifies hydrogen and the other signifies hydrogen, halogen, hydroxy or lower alkoxy, R6 signifies hydrogen or lower alkyl and R7 signifies hydrogen, hydroxy, lower alkyl or lower alkoxy, and either R8 signifies hydrogen, lower alkyl, lower alkenyl, aryl- -(lower alkyl) or acyl and R9 together with R signifies an additional bond, or R9 signifies lower alkyl, lower alkenyl or aryl-(lower alkyl) and R8 together with R signifies an additional bond, with the provisos that R4 or R5 does not signify hydroxy when R7 signifies lower alkoxy and/or R8 signifies acyl, and that R7 does not signify hydroxy when R4 or R5 signifies lower alkoxy and/or R8 signifies acyl, and their pharmaceutically acceptable acid addition salts have valuable therapeutic properties and are especially suitable for use as analgesics. These compounds can be manufactured according to various processes starting from intermediates which are partially novel and can be brought into galenical administration forms.
383138
Gowling Lafleur Henderson Llp
Hoffmann-La Roche Limited
LandOfFree
¬(2-phenylamino-1-imidazolidinyloxy)methyl| pyridine 1-oxide... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with ¬(2-phenylamino-1-imidazolidinyloxy)methyl| pyridine 1-oxide..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and ¬(2-phenylamino-1-imidazolidinyloxy)methyl| pyridine 1-oxide... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1173170