2-(phenylamino)benzimidazole derivatives and their use as...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 235/30 (2006.01) A61K 31/4184 (2006.01) A61P 1/06 (2006.01) A61P 9/04 (2006.01) A61P 11/06 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2612922

This invention relates to 2-(phenylamino) benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in the preparation of medicaments and to pharmaceutical compositions comprising the compounds of the invention.

La présente invention concerne des nouveaux dérivés de 2-(phenylamino)benzimidazole utilisés en tant que modulateurs des canaux de potassium activés par le calcium à faible conductance (canaux SK). Un autre aspect de cette invention concerne l'utilisation de ces composés dans une méthode thérapeutique, ainsi que des compositions pharmaceutiques comprenant les composés de cette invention.

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