2-piperazino-pteridines, processes for the preparation...

Details 2-piperazino-pteridines, processes for the preparation... 2-piperazino-pteridines, processes for the preparation...

C - Chemistry, Metallurgy

07

D

260/242.1

C07D 475/08 (2006.01) C07D 475/06 (2006.01)

Patent

CA 1233179

Abstract New 2-piperazino-pteridines of general formula Image (I) are described wherein R1 represents a phenylalkylamino, alkylamino or dialkylamino group, a piperidino, morpholino, thiomorpholino or 1-oxidothiomorpholino group, R2 represents a dialkylamino, piperidino, morpholino, thiomorpholino or 1-oxidothiomorpholino group and R3 represents a halogen atom, an alkoxy, alkylthio, phenylalkoxy or phenylalkylthio group, wherein the alkyl moiety may contain from 1 to 3 carbon atoms, and the acid addition salts thereof, particularly the physiologically acceptable acid addition salts thereof which have valuable pharmacological properties, particularly antithrombotic and metastasis- inhibiting effects. Processes for preparing the compounds of formula (I) are also described.

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