2-piperidone derivatives as prostaglandin agonists

Details 2-piperidone derivatives as prostaglandin agonists 2-piperidone derivatives as prostaglandin agonists

C - Chemistry, Metallurgy

07

D

C07D 211/76 (2006.01) A61K 31/45 (2006.01) A61P 19/08 (2006.01)

Patent

CA 2511255

The invention provides compounds of the Formula (I): wherein m, n, A, X, Y, Z, R1, R2, R4, R6, R7, R8, R9 and R10 are as defined in the desription and claims, and pharmaceutically acceptable salts, solvates, prodrugs, single isomers or racemic or non-racemic mixture of isomers thereof. The invention also provides methods for preparing, compositions comprising, and methods for using compounds of formula I.

L'invention concerne des composés représentés par la formule (I) dans laquelle m, n, A, X, Y, Z, R1, R2, R4, R6, R7, R8, R9 et R10 sont tels que définis dans la description et les revendications, ainsi que des sels, des solvates, des promédicaments, des isomères simples ou un mélange racémique ou non racémique d'isomères de ceux-ci, acceptables d'un point de vue pharmaceutique. L'invention concerne également des méthodes de préparation des composés représentés par la formule I, ainsi que des compositions contenant lesdits composés et des méthodes d'utilisation de ceux-ci.

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