C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/16 (2006.01) A61K 31/70 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2460911
The invention provides novel class of 2-alkynlademosine derivatives, substituted at the ethyn-2-yl position by substituted cycloalkyl and hetrocyclic moieties. The compounds of the invention have general formula (I): (see formula I) wherein X, R1, R2, R7 and Z are as described herein. The present invention also provides a method for inhibiting the inflammatory response in a mammal, such as a human subject, and protecting the tissue subject to the response, by administering an effective amount of one or more compounds of the invention.
La présente invention concerne des composés de formule générale (I), dans laquelle : X, R?1¿, R?2¿, R?7¿ et Z sont tels que définis dans la description.
Figler Robert Alan
Linden Joel M.
Macdonald Timothy L.
Murphree Lauren Jean
Rieger Jayson M.
Mbm Intellectual Property Law Llp
University Of Virginia Patent Foundation
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