C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/497 (2006.01) A61P 1/04 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2650553
The invention provides compounds of formula (I) wherein R1, R3, R4, R5, R14, X and W are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of human neutrophil elastase.
L'invention concerne des composés de formule (1) dans laquelle R1, R3, R4, R5, R14, X et W sont définis dans la spécification, ainsi que leurs isomères optiques, racémates et tautomères et leurs sels pharmaceutiquement acceptables. Elle concerne également des processus de leur préparation, des compositions pharmaceutiques les contenant et leur utilisation en thérapie. Les composés sont des inhibiteurs de l'élastase neutrophile humaine.
Hansen Peter
Ivarsson Marianne
Lawitz Karolina
Lonn Hans
Nikitidis Antonios
Astrazeneca Ab
Fetherstonhaugh & Co.
LandOfFree
2-pyrazinone derivatives for the treatment of disease or... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-pyrazinone derivatives for the treatment of disease or..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-pyrazinone derivatives for the treatment of disease or... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2087576