2-pyridylmethyl-3h, 7h-quino (8,1-cd) (1,5)...

Details 2-pyridylmethyl-3h, 7h-quino (8,1-cd) (1,5)... 2-pyridylmethyl-3h, 7h-quino (8,1-cd) (1,5)...

C - Chemistry, Metallurgy

07

D

260/238.9

C07D 498/06 (2006.01)

Patent

CA 1048022

ABSTRACT This invention relates to 2-substituted-3H,7H-quino- [8,1-cd][1,5]benzoxazepin-3-one compounds of the formula I Image or Image II wherein Z is hydrogen, lower alkyl, lower alkoxy, bromo, chloro or di(lower alkyl)amino-lower alkoxy and X and Y are hydrogen, chloro, bromo, trifluoromethyl, di(lower alkyl)- sulfonamido, lower alkyl or lower alkoxy, provided that at least one of X and Y is hydrogen, and pharmaceutically acceptable acid addition salts thereof and processes for preparing these compounds. Compounds of Formula I are useful in the treatment of inflammation.

200532

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