2-(quinolonyl)-fused heterocycles as androgen receptor...

Details 2-(quinolonyl)-fused heterocycles as androgen receptor... 2-(quinolonyl)-fused heterocycles as androgen receptor...

C - Chemistry, Metallurgy

07

D

C07D 491/04 (2006.01) A61K 31/4738 (2006.01) A61P 5/00 (2006.01) C07D 215/227 (2006.01) C07D 221/00 (2006.01) C07D 265/00 (2006.01) C07D 279/00 (2006.01) C07D 319/00 (2006.01) C07D 498/04 (2006.01) C07D 498/06 (2006.01) C07D 498/10 (2006.01) C07D 513/04 (2006.01) C07D 513/06 (2006.01)

Patent

CA 2484340

The present invention is directed to novel 2-(quinolonyl)-fused heterocyclyl derivatives of the general formula (I) wherein R1, R2, R3, R3a, R4, R5, R6 and R7 are as herein defined, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

L'invention concerne de nouveaux dérivés hétérocyclyles à fusion 2-(quinolonyle) représentés par la formule générale (I) dans laquelle R?1¿, R?2¿, R?3¿, R?3a¿, R?4¿, R?5¿, R?6¿ et R?7¿ sont tels que définis dans le descriptif, des compositions pharmaceutiques contenant ces dérivés, ainsi que leur utilisation pour le traitement de troubles et d'états pathologiques modulés par le récepteur d'androgènes.

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