2-substitued 5,6-diaryl-pyrazine derivatives as cb1 modulators

Details 2-substitued 5,6-diaryl-pyrazine derivatives as cb1 modulators 2-substitued 5,6-diaryl-pyrazine derivatives as cb1 modulators

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4965 (2006.01) A61K 31/497 (2006.01) A61P 1/00 (2006.01) A61P 3/04 (2006.01) A61P 5/00 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 37/00 (2006.01) C07D 209/44 (2006.01) C07D 211/56 (2006.01) C07D 211/98 (2006.01) C07D 241/24 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2527033

The present invention relates to 5, 6-diaryl-pyrazine-2-carboxamide and- 2- ester derivatives and processes for preparing such compounds, their use in the treatment of obesity, psychiatric and neurological disorders, to methods for their therapeutic use and to pharmaceutical compositions containing them. The compounds are cannabinoid receptor 1 (CB1) modulators.

La présente invention concerne des composés représentés par la formule (I) et des procédés de fabrication de ces composés, leur utilisation dans le traitement de l'obésité, de troubles psychiatriques et neurologiques, des procédés d'utilisation thérapeutique de ces composés, et des compositions pharmaceutiques les contenant.

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