2-substituted-1-deaza purine derivatives with adenosine...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2579303

The present invention relates to 2-substituted-1 -deaza purine derivatives as adenosine receptor modulating agents, to methods for the preparation of these compounds and to novel intermediates useful for the synthesis of sai d purine derivatives. The compounds have the general formula (1) wherein the symbols have the meanings given in the specification.

La présente invention concerne des dérivés de 1-deaza purine 2-substitués, utilisés comme agents modulant le récepteur de l'adénosine, ainsi que leurs méthodes de préparation et de nouveaux produits intermédiaires pouvant être utilisés pour la synthèse de ces dérivés de purine. Ces composés sont représentés par la formule générale (1) dont les symboles désignent des éléments définis dans la description de la présente demande.

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