2-substituted-1-hydroxyindoles

Details 2-substituted-1-hydroxyindoles 2-substituted-1-hydroxyindoles

C - Chemistry, Metallurgy

07

D

C07D 209/30 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2048001

-0- 2-SUBSTITUTED-1-HYDROXYINDOLES Abstract of the Disclosure The present invention relates to 2-substituted-1-hydroxyindoles of the following formula: Image wherein, R1 is an electron withdrawing group, R2 is an alkenyl having 2-10 carbon atoms, an N-substituted .alpha.-iminobenzyl group wherein the substituents are selected from the group consisting of phenyl, anilino and dimethylamino, an unsubstituted aromatic group, and an aromatic group having meta or para substituents which are nitro, trifluoromethyl, fluoro, formyl, hydroxyiminomethyl and carbamoyl, R3 is a halogen atom, and n is 0, 1, or 2, provided that when R2 is either phenyl or nitro substituted phenyl and n is 0, then R1 is not cyano.

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