2-substituted...

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C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61P 15/00 (2006.01) C07C 63/10 (2006.01) C07D 207/00 (2006.01) C07D 207/34 (2006.01) C07D 209/00 (2006.01) C07D 239/00 (2006.01)

Patent

CA 2528008

The invention relates to 2-substituted phenyl-5,7-dihydrocarbyl-3,7- dihydropyrrolo[2,3-d]pyrimidin-4-one derivatives, their preparation and the pharmaceutical compositions containing them. The invention also relates to the use of these derivatives in preparing medicines, which can treat sexual dysfunction of animals including human (male and female), especially erectile dysfunction of male and the diseases in which the function of phospholipase 5 (cGMP PDE5) is involved.

L'invention concerne des composés correspondant à la formule (I), leur préparation et les compositions pharmaceutiques les contenant. L'invention concerne également l'utilisation de ces composés dans la préparation de médicament destiné à traiter une dysfonction sexuelle chez les animaux (mâles et femelles) et chez l'homme ou la femme, en particulier une dysérection et les maladies dans lesquelles la fonction de la phospholipase 5 (cGMP PDE5) est impliquée.

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