2-substituted 4,5-diphenyl-imidazoles

Details 2-substituted 4,5-diphenyl-imidazoles 2-substituted 4,5-diphenyl-imidazoles

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/395 (2006.01) C07D 233/84 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2071497

2071497 9109030 PCTABS00005 Imidazole derivatives of the formula (I): [DPIM]-S-W-Y, wherein [DPIM] represents a group of formula (DPIM), wherein R and R1 represent hydrogen, halogen or alkyl, W represents straight chain alkylene of 1 to 6 carbon atoms optionally substituted by alkyl, Y represents a group of formulas (II), (III), (IV), (V), (VI) and salts thereof, are inhibitors of acyl coenzyme-A:cholesterol-O-acyl transferase useful for the conditions such as atherosclerosis, hyperlipidaemia, cholesterol or ester storage disease and atheroma in vein grafts.

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