C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/454 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07D 401/06 (2006.01)
Patent
CA 2536929
The present invention discloses compounds of formula (I); wherein Ar, Y, m, n, R1 and R4 are herein defined, said compounds being novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
L'invention concerne des composés de formule (I); dans laquelle Ar, Y, m, n, R?1¿ et R?4¿ ont les significations incluses, lesdits composés étant de nouveaux antagonistes de l'hormone de concentration de la mélanine (MCH), et des procédés de production desdits composés. L'invention concerne en outre des compositions pharmaceutiques comprenant lesdites antagonistes de MCH ainsi que des procédés d'utilisation dans le traitement de l'obésité, de troubles métaboliques, et de troubles alimentaires comme l'hyperphagie et le diabète.
Burnett Duane A.
Caplen Mary Ann
Greenlee William J.
Guo Tao
Hunter Rachael
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pharmacopeia Inc.
Pharmacopeia Drug Discovery Inc.
Schering Corporation
LandOfFree
2-substituted benzimidazole piperidines analogs as selective... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-substituted benzimidazole piperidines analogs as selective..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-substituted benzimidazole piperidines analogs as selective... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1365897