C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/54 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) C07D 233/84 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2295021
This invention relates to substituted imidazoles of Formula (I), pharmaceutical compositions containing them, methods of using them and intermediates useful in their manufacture. The compounds of the invention modulate the production of a number of inflammatory cytokines, and are useful in the treatment of diseases associated with the production of inflammatory cytokines.
L'invention porte sur des imidazoles substituées de formule (I), sur des préparations pharmaceutiques les contenant, sur leurs modes d'utilisation, et sur leurs intermédiaires de fabrication. Les composés de l'invention, qui modulent la production de certaines cytokines inflammatoires, servent à traiter les maladies associées à la production desdites cytokines.
Beers Scott A.
Malloy Elizabeth A.
Wachter Michael P.
Wu Wei
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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