2-substituted or unsubstituted aminocarbonyloxyalkyl- 1,...

Details 2-substituted or unsubstituted aminocarbonyloxyalkyl- 1,... 2-substituted or unsubstituted aminocarbonyloxyalkyl- 1,...

C - Chemistry, Metallurgy

07

D

260/278.1, 260/2

C07D 211/90 (2006.01) C07D 401/00 (2006.01) C07D 413/00 (2006.01)

Patent

CA 1196332

ABSTRACT OF THE DISCLOSURE: Novel compounds having vasodilation and hypotensive effects are represented by the formula Image (I) where R1 is halogen, nitro, cyano or lower alkoxy; each of R2 and R3 is lower alkyl, lower haloalkyl, lower alkoxyalkyl, aralkyloxyalkyl, aryloxyalkyl, lower alkenoxyalkyl, N,N-di-lower alkylaminoalkyl, N-lower alkyl-N-aralkylaminoalkyl, piperidylalkyl, 4-lower alkyl piperazinylalkyl, norpholinoalkyl or 1-pyrrolidinylalkyl; R4 is lower alkyl; A is lower alkylene; and R5 is hydrogen, lower alkyl, cycloalkyl of 3 to 7 carbon atoms, or aryl unsubstituted or substituted by one or two substituents selected from halogen, nitro, lower alkyl, lower alkoxy, di-lower alkylamino and cyano. Also disclosed are processes for their preparation.

401301

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