C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/28 (2006.01) A61K 31/4184 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) C07D 405/14 (2006.01) C07D 471/12 (2006.01)
Patent
CA 2577748
The invention relates to 2-sulfanyl-benzoimidazol-1-yl-acetic acid derivatives and their use as potent "chemoattractant receptor-homologous molecule expressed on Th2 cells" antagonists in the treatment of prostaglandin mediated diseases, to pharmaceutical compositions containing these derivatives and to processes for their preparation.
L'invention concerne des dérivés de l'acide 2-sulfanyl-benzoimidazol-1-yl-acétique ainsi que leur utilisation en tant que puissants antagonistes de la "molécule homologue au récepteur à fonction chimioattractive exprimée sur les cellules Th2" dans le traitement de maladies induites par la prostaglandine. L'invention concerne également des compositions pharmaceutiques contenant lesdits dérivés ainsi que des procédés de préparation de ces dernières.
Fretz Heinz
Gude Markus
Hilpert Kurt
Potjier Julien
Riederer Markus
Actelion Pharmaceuticals Ltd
Gowling Lafleur Henderson Llp
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