2-tetrahydrofurfuryl-6,7-benzomorphanes, their acid addition...

Details 2-tetrahydrofurfuryl-6,7-benzomorphanes, their acid addition... 2-tetrahydrofurfuryl-6,7-benzomorphanes, their acid addition...

C - Chemistry, Metallurgy

07

D

260/237.87

C07D 405/06 (2006.01) C07D 221/26 (2006.01) C07D 307/10 (2006.01)

Patent

CA 1049511

ABSTRACT OF THE DISCLOSURE The invention relates to novel 2-tetrahydrofurfuryl- 6,7-benzomorphanes the acid addition salts thereof as well as to processes for their preparation. The novel compounds possess a therapeutically useful effect upon the central nervous system. In particular, the novel compounds possess an especially pronounced analgesic effect. The most effective compounds have been found to possess an analgesic effect ten to thirty times greater than morphine. Processes for the production of the novel compounds are described and examples of certain of the novel compounds are given. Pharmaceutical compositions containing the novel compounds are described and exemplified.

221554

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