2-thio-substituted imidazole derivatives and their use in...

Details 2-thio-substituted imidazole derivatives and their use in... 2-thio-substituted imidazole derivatives and their use in...

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2501849

The invention relates to 2-thio-substituted imidazole derivatives of formula (I), wherein the radicals R1, R2, R3 and m have the meanings as cited in the description. The inventive compounds comprise an immunomodulatory action and/or an action that inhibits the release of cytokines and are thus suited for treating diseases associated with a disorder of the immune system.

L'invention concerne des dérivés d'imidazol 2-thio-substitués de formule (I), dans laquelle les restes R?1¿, R?2¿ et R?3¿ et m ont la signification mentionnée dans la description. Les composés selon l'invention ont un effet immunomodulateur et/ou un effet inhibant la libération de la cytokine et s'utilisent de ce fait dans le traitement d'affections en rapport avec des troubles du système immunitaire.

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