2' -trifluoromethyl cinchonine and cinchonidine derivatives

Details 2' -trifluoromethyl cinchonine and cinchonidine derivatives 2' -trifluoromethyl cinchonine and cinchonidine derivatives

C - Chemistry, Metallurgy

07

D

260/271.3

C07D 453/04 (2006.01) A61K 31/49 (2006.01) C07D 215/12 (2006.01) C07D 215/18 (2006.01) C07D 215/233 (2006.01) C07D 453/02 (2006.01)

Patent

CA 1039283

Abstract Compounds of the general formulae Image and Image I II wherein R1 is halogen or trifluoromethyl and R2 is ethyl or vinyl, enantiomers and racemates thereof, as well as their prepa- ration are disclosed. These compounds are useful as anti- malaria agents.

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