C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 259/14 (2006.01) A61K 31/155 (2006.01)
Patent
CA 2389378
The present invention relates to an inhibitor for production of 20-hydroxyeicosatetraenoic acid, comprising, as an effective ingredient, specific hydroxyformamidine derivatives or pharmaceutically-acceptable salts thereof. The inhibitors according to the present invention are useful as therapeutic agents for kidney diseases, cerebrovascular diseases, or circulatory diseases. In addition, the present invention also provides novel hydroxyformamidine derivatives or pharmaceutically-acceptable salts thereof.
Cette invention se rapporte à un inhibiteur pour la production d'acide 20-hydroxyeicosatétraénoïque (HETE) qui comprend comme principe actif un dérivé d'hydroxyformamidine spécifique ou un sel de ce dérivé acceptable sur le plan pharmacologique. Cet inhibiteur est utile notamment comme remède contre les affections hépathiques, les affections cérébrovasculaires ou les affections circulatoires. Cette invention concerne également ce nouveau dérivé d'hydroxyformamidine ou son sel acceptable sur le plan pharmacologique.
Amada Hideaki
Ishii Takaaki
Kobayashi Yuko
Miyata Noriyuki
Sato Masakazu
Taisho Pharmaceutical Co. Ltd.
Torys Llp
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