22196, a novel human aminopeptidase

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/57 (2006.01) A01K 67/027 (2006.01) A61K 38/48 (2006.01) C07K 16/40 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/48 (2006.01) C12N 9/64 (2006.01) C12N 15/00 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2382808

The present invention relates to a newly identified human aminopeptidase. The invention also relates to polynucleotides encoding the aminopeptidase. The invention further relates to methods using the aminopeptidase polypeptides and polynucleotides as a target for diagnosis and treatment in aminopeptidase- related disorders. The invention further relates to drug-screening methods using the aminopeptidase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the aminopeptidase polypeptides and polynucleotides. The invention further relates to procedures for producing the aminopeptidase polypeptides and polynucleotides.

L'invention porte sur: une aminopeptidase humaine nouvellement identifiée; sur les polynucléotides codant pour ladite aminopeptidase; sur des procédés d'utilisation des polypeptides et polynucléotides de ladite aminopeptidase comme cibles pour le diagnostic et le traitement de troubles liés à ladite aminopeptidase; sur des procédés de criblage utilisant des polypeptides et polynucléotides de ladite aminopeptidase pour en identifier les agonistes et antagonistes à des fins de diagnostic et de traitement; sur les agonistes et antagonistes des polypeptides et polynucléotides de ladite aminopeptidase; et sur des processus de production des polypeptides et polynucléotides de ladite aminopeptidase.

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