23-0-substituted carbamoyl-23-demycinosyldesmycosin

Details 23-0-substituted carbamoyl-23-demycinosyldesmycosin 23-0-substituted carbamoyl-23-demycinosyldesmycosin

C - Chemistry, Metallurgy

07

H

260/230.37

C07H 17/08 (2006.01)

Patent

CA 1218987

ABSTRACT OF THE DISCLOSURE The invention provides compounds of the formula Image [1] wherein R1 is lower alkyl, lower alkoxycarbonyl-lower alkyl, phenyl, phenyl substituted by one or more lower alkyl groups or a halogen atom, phenyl-lower alkyl optionally substituted in its side chain by a lower alkyl or lower alkoxycarbonyl, thienyl- methyl or thizolyl group, R2 is a hydrogen atom or a lower alkyl group, or Image constitutes a 3- to 7-membered nitrogen atom containing heterocyclic ring in which R1 and R2 are connected, R3 is a hydrogen atom or a hydroxyl group, and X is an oxygen or sulfur atom; or a non-toxic salt thereof. These compounds are antibiotics having stronger antibacterial activity than that of known clinically used macrolide antibiotics, and is effective against macrolide antibiotic-resistant bacterial strains. The compounds are also useful as feed additives and growth stimulants.

419804

Affiliated with

Also associated with

Rating

23-0-substituted carbamoyl-23-demycinosyldesmycosin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 23-0-substituted carbamoyl-23-demycinosyldesmycosin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 23-0-substituted carbamoyl-23-demycinosyldesmycosin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1280745