23-deoxy derivatives of ll-f28249 compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 493/22 (2006.01) A01N 43/90 (2006.01) A01N 49/00 (2006.01) A23K 1/17 (2006.01) A61K 31/70 (2006.01) C07H 19/01 (2006.01)

Patent

CA 1340104

The present invention relates to novel derivatives of LL-F28249 compounds. These LL-F28249 compounds preferably are derived via a controlled microbiological fermentation of Streptomyces cyaneogriseus subsp. non-cyanogenus having deposit accession number NRRL 15773. The 23-deoxy derivatives have the 23-hydroxy group replaced by hydrogen. The novel derivatives of the present invention possess activity as anthelmintic, ectoparasitic, insecticidal, acaricidal and nematicidal agents. They also are useful in areas of human and animal health and in agricultural crops.

546559

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