25-alkylcholesterol derivatives

Details 25-alkylcholesterol derivatives 25-alkylcholesterol derivatives

C - Chemistry, Metallurgy

07

J

260/60

C07J 9/00 (2006.01) C07J 53/00 (2006.01)

Patent

CA 1113086

Abstract of the Disclosure The present invention relates to the prepartation of derivatives of 25-alkylcholesterol which display valuable pharmacological properties in that they inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, an enzyme which controls the rate at which cholesterol is synthesized in mammalian liver (one of the two principal sources of serum cholesterol). .

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