25-halocholest-5-ene-3b&', 22-diols and esters thereof

Details 25-halocholest-5-ene-3b&', 22-diols and esters thereof 25-halocholest-5-ene-3b&', 22-diols and esters thereof

C - Chemistry, Metallurgy

07

J

260/60

C07J 9/00 (2006.01) C07C 29/36 (2006.01) C07F 7/18 (2006.01) C07J 53/00 (2006.01)

Patent

CA 1144539

Case 2160 Chorvat 25-HALOCHOLEST-5-ENE-3.beta.,22-DIOLS AND ESTERS THEREOF ABSTRACT OF THE DISCLOSURE 25-halocholest-5-ene-3.beta.,22-diols and esters thereof which inhibit the activity of 3-hydroxy-3-methyl- glutaryl coenzyme A reductase and inhibit the formation of serum cholesterol and their preparation from 3.alpha.,5-cyclo- 6.beta.-methoxy-23,24-dinor-5.alpha.-cholan-20-al are disclosed.

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