2h-phthalazin-1-ones and methods for use thereof

Details 2h-phthalazin-1-ones and methods for use thereof 2h-phthalazin-1-ones and methods for use thereof

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/502 (2006.01) A61K 31/5025 (2006.01) A61P 35/00 (2006.01) C07D 237/32 (2006.01) C07D 237/34 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2456985

The present invention provides compounds comprising a bicyclic aryl moiety, such as 2H-phthalazin-1-one or derivatives thereof, compositions comprising the same, and methods for producing and using the same. In particular, the present invention provides compounds of the formula: (I) or a pharmaceutically acceptable salt, a hydrate, a solvate, or a prodrug thereof; where Q1, Q2 and Y are those defined herein.

L'invention concerne des composés comprenant une fraction aryle bicyclique, p. ex. 2H-phtalazine-1-one ou ses dérivés, des compositions contenant ces composés et des procédés de production et d'utilisation de ceux-ci. Elle concerne en particulier des composés représentés par la formule (I) ou un sel pharmaceutiquement acceptable, un hydrate, un solvate, ou un promédicament de ceux-ci, Q?1¿, Q?2¿ et Y étant définis dans la demande.

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