3-(1,2,5-trisubstituted imidazolidinone)azetidinone...

C - Chemistry – Metallurgy – 07 – D

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260/304, 260/305

C07D 403/04 (2006.01) C07D 413/04 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1308725

Abstract 2,5-Disubstituted oxazolidin-4-one-3-ylacetyl chlorides and 1,2,5-substituted imidazolidin-4-one-3-yl- acetyl chlorides function as chiral auxiliary moieties in the asymmetric cycloaddition with aldimines to pro- vide cis-azetidinones. The azetidinones are useful intermediates in the preparation of antibiotics.

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