3-(1-(4-phenyl-4-oxobutyl)piperidyl-4-yl) urea compounds

Details 3-(1-(4-phenyl-4-oxobutyl)piperidyl-4-yl) urea compounds 3-(1-(4-phenyl-4-oxobutyl)piperidyl-4-yl) urea compounds

C - Chemistry, Metallurgy

07

D

260/278, 260/292

C07D 211/18 (2006.01) C07D 211/58 (2006.01)

Patent

CA 1046065

ABSTRACT This invention provides processes for preparing 3-[piperidino]-ureas and -thioureas which are substituted on the nitrogen of the piperidine ring by a 4-oxo-butylene group carrying a phenyl or substituted phenyl substituent. The 1-nitrogen or the urea or thiorea may also carry an aryl, aryl lower alkyl, aroyl, lower alkyl or cycloalkyl substituent; the 3-nitrogen may also carry lower alkyl substituent. These compounds exhibit pharmacological activity such as action on the cardiovascular system.

220677

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