3,11-dihydro-6h-pyrazolo (1.5-a) pyrazolo (4'3':5,6)...

Details 3,11-dihydro-6h-pyrazolo (1.5-a) pyrazolo (4'3':5,6)... 3,11-dihydro-6h-pyrazolo (1.5-a) pyrazolo (4'3':5,6)...

C - Chemistry, Metallurgy

07

D

260/242.01

C07D 471/22 (2006.01)

Patent

CA 1069892

Abstract New 3,11-dihydro-6H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]- pyrido[4,3-d]pyrimidin-6-one and new derivatives thereof, use- ful as antiinflammatory agents, have the general formula Image wherein R1 and R3 each is hydrogen, lower alkyl, phenyl or phenyl-lower alkylene; R2, R4 and R6 each is hydrogen or lower alkyl; R5 is hydrogen, lower alkyl, phenyl-lower alkylene, ben- zoyl, substituted benzoyl wherein the phenyl substituent is halogen, lower alkyl or lower alkoxy, lower alkanoyl, lower alkoxy-lower alkylene, lower alkylthio-lower alkylene, amino- lower alkylene or Image alkylene wherein R7 and R8 each is lower alkyl or join in forming piperidine, morpholine, thia- morpholine or piperazine; and acid addition salts thereof.

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