C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/75 (2006.01) A61K 31/4412 (2006.01) A61K 31/4436 (2006.01) A61K 31/4439 (2006.01) C07D 401/06 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2588713
The present invention provides a compound of formula (I): wherein R1, R2, R3,R4,and R5 are as defined herein. The present invention also provides pharmaceutical compositions and methods using such compositions for treating a caspase-mediated diseases and processes for preparing the compounds of the invention.
La présente invention se rapporte à un composé représenté par la formule (I), dans laquelle R1, R2, R3,R4et R5 sont tels que définis dans le descriptif de l'invention. L'invention a également trait à des compositions pharmaceutiques et à des procédés d'utilisation de telles compositions pour traiter une maladie liée aux caspases, ainsi qu'à des procédés de préparation des composés selon l'invention.
Charrier Jean-Damien
Knegtel Ronald
Mortimore Michael
Studley John R.
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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