3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-...

Details 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-... 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2537054

The present invention relates to the compound ethyl 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl- 1H-benzimidazole-5-carbonyl)-pyridin-2-yl-amino]-propionate-methanesulphonate in the crystalline modifications I and II and as the hemihydrate and the use thereof as a pharmaceutical composition.

La présente invention concerne le composé éthylester-méthansulfonate d'acide 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phénylamino]-méthyl}-1-méthyl-1<I>H</I>-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionique dans les modifications cristallines I et II et en tant que semi-hydrate, ainsi que son utilisation en tant que médicament.

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