3-(2-hydroxy-3-aminopropyl)-pyridoxine

Details 3-(2-hydroxy-3-aminopropyl)-pyridoxine 3-(2-hydroxy-3-aminopropyl)-pyridoxine

Category

C - Chemistry, Metallurgy

Subcategory

07

Subsubcategory

D

CPC

260/290.6

IPC codes

C07D 213/67 (2006.01) C07D 213/66 (2006.01) C07D 491/04 (2006.01)

Type

Patent

Patent number

CA 1152080

Description

ABSTRACT OF THE DISCLOSURE: Novel pyridoxine derivatives represented by the general formula: Image in which: R represents a radical Image , -CH2-(CH2)n-CH2-OR2 or Image in which n represents O or 1, X and X1, which are different, represent hydrogen or methyl, Y represents hydrogen or methyl and R2 represents a phenyl group non-substi- tuted or bearing one or two substituents selected from the group consisting of fluorine, chlorine and bromine and of the radicals methyl, ethyl, n-propyl, isopropyl and methoxy, the radicals R1 are the same and represent hydrogen or a radical of formula Image in which R3 represents a straight-chain alkyl radical having from 1 to 4 carbon atoms and pharma- ceutically acceptable acid addition salts thereof. These compounds present .alpha.-antiadrenergic properties some of them also presenting .beta.-antiadrenergic, antihypertensive and central depressant effects.

Application Number

377739

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