C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/403 (2006.01) A61K 31/4178 (2006.01) A61P 25/00 (2006.01) C07D 209/52 (2006.01)
Patent
CA 2746444
In one aspect, the invention relates to compounds which are useful as inhibitors of glycine type 1 transporter (GIyT1) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GIyT1) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Selon un aspect, la présente invention concerne des composés qui sont utiles en tant quinhibiteurs de lactivité du transporteur de glycine 1 (GIyTl); des procédés synthétiques pour fabriquer les composés; des compositions pharmaceutiques comportant les composés; et des procédés pour traiter des troubles associés à lactivité du transporteur de glycine 1 (GIyTl) mettant en uvre les composés et compositions. Cet abrégé est fourni pour donner un bref aperçu pour les besoins de la recherche dans le domaine particulier et ne doit aucunement limiter la portée de la présente invention.
Conn P. Jeffrey
Jones Carrie K.
Lindsley Craig W.
Niswender Colleen M.
Sheffler Douglas J.
Torys Llp
Vanderbilt University
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