3,3'-diindolylmethane immune activating compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/404 (2006.01) A61K 38/19 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2586582

The invention provides immune response activating compositions and methods of use. The general methods deliver an immune response activator to a patient determined to be in need thereof, comprising the steps of: (a) administering to the patient a predetermined amount of an immune response activating, optionally substituted DIM; and (b) detecting in the patient a resultant immune response activation, such as an increase in T-cell proliferation, NO production, cytokine production, cytokine receptor expression, or cytokine signaling.

L'invention concerne des compositions d'activation de la réponse immune et des procédés d'utilisation de celles-ci. Les procédés consistent à administrer un activateur de la réponse immune à un patient nécessitant un tel traitement et comprennent les étapes consistant: (a) à administrer au patient une quantité prédéterminée d'un DIM d'activation de la réponse immune, éventuellement substitué; et (b) à détecter chez le patient une activation de la réponse immune obtenue, telle qu'une augmentation de la prolifération de lymphocytes T, de la production de NO, de la production de cytokines, de l'expression du récepteur des cytokines ou de la signalisation des cytokines.

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