3,3-disubstituted tri-and tetracyclic indolin-2-ones useful...

C - Chemistry – Metallurgy – 07 – D

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C07D 498/06 (2006.01) A61K 31/395 (2006.01) C07D 471/06 (2006.01) C07D 487/06 (2006.01) C07D 513/06 (2006.01)

Patent

CA 2146000

Compounds of formula (I) have been shown to enhance the release of the neurotransmitter acetylcholine, and thus may be useful as chemical intermediates and as pharmacological agents in the treatment of diseases of man, such as in Alheimer's Dis- ease and other conditions involving learning and cognition, where subnormal levels of this neurochemical are found. The com- pounds of this invention have the structure shown in formula (I).

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