3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyrimidine...

Details 3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyrimidine... 3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyrimidine...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2747287

The invention relates to the compounds of formula I, where R1, R2, R3, R3', R4 are as defined in claim 1, and are inhibitors of tyrosine kinases, particularly of Met kinase, and can be used for treating tumors, among other uses.

La présente invention concerne des composés qui, d'une part sont représentés par la formule (I), en l'occurrence des inhibiteurs des tyrosine-kinases, et plus particulièrement de la kinase Met, et qui, d'autre part conviennent notamment au traitement de tumeurs. Dans cette formule, R1, R2, R3, R3 et R4 ont les significations données dans la 1ère revendication.

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