3,3'-spiroindolinone derivatives and their use for cancer

Details 3,3'-spiroindolinone derivatives and their use for cancer 3,3'-spiroindolinone derivatives and their use for cancer

C - Chemistry, Metallurgy

07

D

C07D 471/10 (2006.01) A61K 31/4747 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2758640

There are provided compounds of the formula (I) or a pharmaceutically acceptable salt or ester thereof wherein X, Y, W, W',V, V', V", R1, R2 and R3 are as herein described. The compounds have utility as antiproliferative agents, especially, as anticancer agents.

L'invention porte sur des composés de formule (I) ou un sel ou un ester pharmaceutiquement acceptable de ceux-ci où X, Y, W, W',V, V', V", R1, R2 et R3 sont tels que décrits présentement. Les composés sont utiles en tant qu'agents antiprolifératifs, notamment en tant qu'agents anticancéreux.

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