3,3'-spiroindolinone derivatives as anticancer agents

C - Chemistry – Metallurgy – 07 – D

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C07D 471/10 (2006.01) A61K 31/438 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2751767

There are provided compounds of the Formula (I), or a pharmaceutically acceptable salt or ester thereof wherein X, Y, R1, R2 are as herein described. The compounds have utility as anti- proliferative agents, especially, as anticancer agents.

L'invention concerne des composés représentés par la formule (I), ou un sel pharmaceutiquement acceptable ou un ester de ceux-ci. Dans la formule (I), X, Y, R1, R2 sont tels que présentés dans la description. Ces composés sont utilisés comme agents antiprolifératifs, en particulier comme agents anticancéreux.

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