3- (4-{ ¬4-(4-{ ¬3-(3, 3-dimethyl-1-piperidinyl) propyl|...

Details 3- (4-{ ¬4-(4-{ ¬3-(3, 3-dimethyl-1-piperidinyl) propyl|... 3- (4-{ ¬4-(4-{ ¬3-(3, 3-dimethyl-1-piperidinyl) propyl|...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4545 (2006.01) A61P 11/00 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2634391

The present invention relates to a compound of formula (I), or a salt thereof wherein the naphthalene ring can be substituted in the 2, 3, 4, 5, 6, 7 or 8 position by R1, and R1 represents -CH2CH2COOH or -CH=C(CH3)COOH, and to processes for their preparation, to compositions containing them and to their use in the treatment of various diseases such as allergic rhinitis.

La présente invention concerne un composé de formule (I) ou un sel dudit composé où le cycle naphtalène peut être substitué en position 2, 3, 4, 5, 6, 7 ou 8 par R<SUP>1</SUP>, R<SUP>1</SUP> représentant -CH<SUB>2</SUB>CH<SUB>2</SUB>COOH ou -CH=C(CH<SUB>3</SUB>)COOH, ainsi que des procédés de synthèse dudit composé ou de son sel, des préparations contenant ledit composé ou son sel et leur emploi dans le traitement de diverses maladies telles que la rhinite allergique.

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