3,4,5-substituted piperidines as renin inhibitors

Details 3,4,5-substituted piperidines as renin inhibitors 3,4,5-substituted piperidines as renin inhibitors

C - Chemistry, Metallurgy

07

D

C07D 211/42 (2006.01) A61K 31/445 (2006.01) A61P 9/00 (2006.01) A61P 27/06 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2601108

The application relates to novel substituted piperidines of the general formula (II) in which R1, R2', R2'', R4', X, Z, m and n have the meanings defined in the description, to a process for the preparation thereof and to the use of these compounds as medicines, especially as renin inhibitors.

La présente invention concerne de nouvelles pipéridines substituées représentées par la formule (II) dans laquelle R1, R2', R2'', R4', X, Z, m et n sont tels que définis dans le descriptif, un procédé de préparation de ces nouvelles pipéridines substituées et l'utilisation de ces composés en tant que médicaments, plus spécifiquement en tant qu'inhibiteurs de la rénine. Formule (II)

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