3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives...

Details 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives... 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives...

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/404 (2006.01) A61K 31/4166 (2006.01) A61K 31/437 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61P 35/00 (2006.01) C07D 403/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2438314

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

La présente invention concerne des composés pyrrole substitués 2-indolinone ainsi que des sels pharmaceutiquement acceptables de ces composés qui modulent l'activité de la protéine kinase et qui, de ce fait, devraient contribuer à la prévention et au traitement de troubles cellulaires en rapport avec la protéine kinase tels que le cancer.

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