3-(4-aminophenyl) thienopyrimid-4-one derivatives as mch r1...

Details 3-(4-aminophenyl) thienopyrimid-4-one derivatives as mch r1... 3-(4-aminophenyl) thienopyrimid-4-one derivatives as mch r1...

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2543122

This invention relates to novel arylamines which are antagonists of the melanin-concentrating hormone receptor 1 (MCH R1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in medicines for the treatment of obesity, diabetes, depression, and/or anxiety. Compounds of the invention have the formula:

L'invention concerne des nouvelles arylamines qui sont des antagonistes du récepteur de l'hormone de concentration de la mélanine 1 (MCH R1), des compositions pharmaceutiques les contenant, des procédés pour leur préparation, et leur utilisation dans des médicaments destinés à traiter l'obésité, le diabète, la dépression et/ou l'anxiété. Les composés de l'invention sont représentés par la formule (I).

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